IndustrialPharmacy
The science and technology of large-scale drug manufacturing — from foundational unit operations and mixing through granulation, compression, coating, drying, and particle size reduction to the finished dosage form.
Intro to Unit Operations
Scope and importance of pharmaceutical manufacturing, classification of unit operations, GMP principles, material and energy balances, scale-up concepts, and regulatory frameworks for industrial production.
Mixing & Blending
Mechanisms of mixing (convective, diffusive, shear), tumble blenders, ribbon mixers, high-shear mixers, static mixers, blend uniformity, segregation, and quality control of mixed products.
Tablet Compression
Single-punch and rotary tablet presses, compression force and hardness, tooling types, tablet defects (capping, lamination, sticking), compaction profiles, direct compression, and in-process controls.
Granulation
Wet granulation (high-shear, fluidised-bed), dry granulation (roller compaction, slugging), melt granulation, binders and granulating agents, endpoint determination, and granule characterisation.
Filtration & Clarification
Filter media and filter aids, depth and surface filtration, pressure and vacuum filtration, membrane filtration, sterile filtration, centrifugation, and clarification of pharmaceutical liquids.
Evaporation
Principles of evaporation, types of evaporators (falling film, rising film, wiped film, multiple-effect), heat transfer, vapour recompression, concentration of pharmaceutical solutions, and energy efficiency.
Encapsulation & Coating
Hard and soft gelatin capsule filling, capsule sealing, pan coating, fluidised-bed coating, film coating formulations, enteric coatings, modified-release coatings, and coating defects.
Drying
Moisture content and drying rate curves, tray drying, fluidised-bed drying, spray drying, freeze drying (lyophilisation), infrared and microwave drying, and moisture specifications for pharmaceutical products.
Particle Size Reduction
Principles of size reduction (Kick's, Rittinger's, Bond's laws), ball mills, hammer mills, fluid energy mills, colloid mills, cutter mills, factors affecting milling, and particle size analysis.
Start with Unit 1 — Introduction to Unit Operations and work your way through.