Osmolarity Calculator Suite
Calculate osmolarity for various biological and pharmaceutical solutions
Select Calculator Type
General Osmolarity Calculator
Solutes in Solution
| Solute | Concentration (mmol/L) | Dissociation (i) | Contribution | Action |
|---|---|---|---|---|
| NaCl | 150 | 2 | 300 mOsm/L | |
| Glucose | 5.5 | 1 | 5.5 mOsm/L |
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Common Solutes
General Calculator Info
Osmolarity: Total concentration of osmotically active particles
Formula: Σ(C × i) where C is concentration and i is dissociation factor
Units: mOsm/L (milliosmoles per liter)
Clinical Applications
- • Fluid therapy planning
- • TPN formulation
- • IV compatibility checking
- • Renal function assessment
- • Electrolyte balance monitoring
- • Pharmaceutical formulation
Osmolarity Reference Values
| Solution/Fluid | Osmolarity (mOsm/L) | Tonicity | pH | Clinical Use |
|---|---|---|---|---|
| Normal Saline (0.9% NaCl) | 308 | Isotonic | 5.5 | Fluid resuscitation |
| Lactated Ringer's | 273 | Isotonic | 6.5 | Surgery, burns |
| D5W (5% Dextrose) | 252 | Isotonic (initially) | 4.0 | Free water replacement |
| TPN Standard | 1200-1800 | Hypertonic | 5.5-6.5 | Nutrition support |
| Human Plasma | 275-295 | - | 7.35-7.45 | Physiological reference |