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Pharmacopedia
Calculation Tools
About Us
Drug‑Receptor Binding Affinity Tool
Kd, Ki, IC50 & receptor occupancy
Binding Parameters
Kd (nM)
Ki (nM)
IC50 (nM)
Ligand [L] (nM)
Receptor [R] (nM)
Example Drugs
Fentanyl
Kd 0.1 nM
Propranolol
Kd 1.0 nM
Aspirin
Kd 100 nM
Warfarin
Kd 1000 nM
Penicillin
Kd 10000 nM
Calculate Affinity
Cheng‑Prusoff
Ki = IC₅₀ / (1 + [L]/Kd)
